(1)Hong Kong Sanatorium & Hospital, Medical Physics and Research Department, Happy Valley, Hong Kong SAR China;

¹Princess Margaret Cancer Center, Radiation Oncology, Toronto, Canada; ²Sally Mugabe Hospital, Department of Oncology, Harare, Zimbabwe; ³ Princess Margaret Cancer Centre, Department of Biostatistics, Toronto, Canada; ⁴Princess Margaret Cancer Centre, Department of Biostatistics, Toronto, Canada; ⁵Dalla Lana School of Public Health, University of Toronto, Biostatistics, Toronto, Canada; ⁶ University of California , , Department of Radiation Oncology, San Francisco, USA; ⁷Ghent University Hospital and Ghent University, Department of Radiation Oncology, Ghent, Belgium; ⁸University of Toronto, Radiation Oncology Program, Toronto, Canada

(1)Skåne University Hospital, Dept of Hemathology- Oncology and Radiation Physics, Lund, Sweden;

(1)University Hospital Zurich, Radiation-Oncology, Zurich, Switzerland;

(1)German Cancer Research Center DKFZ, Clinical Cooperation Unit Radiation Oncology, Heidelberg, Germany;(2)University of Heidelberg, Faculty of Physics and Astronomy, Heidelberg, Germany;(3)German Cancer Research Center DKFZ, Medical Physics in Radiation Oncology, Heidelberg, Germany;(4)Heidelberg Institute of Radiation Oncology HIRO, National Center for Radiation Research in Oncology NCRO, Heidelberg, Germany;(5)German Cancer Research Center DKFZ, Division of Medical Physics in Radiology, Heidelberg, Germany;(6)German Cancer Research Center DKFZ, Department of Radiopharmaceutical Chemistry, Heidelberg, Germany;(7)University Hospital Heidelberg, Department of Radiation Oncology, Heidelberg, Germany;(8)German Cancer Research Center, Medical Physics in Radiation Oncology, Heidelberg, Germany;(9)German Cancer Consortium DKTK, partner site, Heidelberg, Germany;(10)Heidelberg Ion-Beam Therapy Center HIT- Heidelberg University Hospital, Department of Radiation Oncology, Heidelberg, Germany;(11)National Center for Tumor diseases NCT, Radiation Oncology and Radiation Therapy, Heidelberg, Germany; (12)Kirchhoff-Institute for Physics, Heidelberg University, Heidelberg,Germany

(1)University Hospital Heidelberg, Department of Radiation Oncology, Heidelberg, Germany;(2)German Cancer Research Center DKFZ- Heidelberg- Germany, Clinical Cooperation Unit Radiation Oncology, Heidelberg, Germany;(3)University of California – San Francisco, Department of Radiation Oncology, San Francisco, USA;