Programme

Overview: This session will address how carrying BRCA mutations may effect reproductive potential, fertility preservation strategies, and the safety of pregnancy. It will address risk reducing surgery and delve into how loco-regional therapy for those diagnosed with breast cancer may be individualised. Factors influencing surgery and the benefits and risks of breast conservation versus mastectomy will be presented taking into account oncological outcomes, genetic risk factors and patient preferences. Decision-making around adjuvant radiotherapy will be discussed including how novel systemic therapies may modify the radiotherapy landscape. Importantly this symposium will include the patient voice to better understand what is most important to young BRCA carriers in terms of treatment goals and unmet needs.

Overview: Over the last 5 years there have been many practice changing developments in the management of endometrial carcinoma. The role of molecular markers, their impact on risk estimation and treatment decisions has evolved. Therefore, the FIGO staging system has been revised in 2023 to include molecular markers. In 2025, the ESGO-ESTRO-ESP guidelines on the management of endometrial carcinoma have been updated according to the latest evidence.

Overview: This symposium will focus on AI and machine learning applications for MRI-guided radiotherapy. Anaïs Barateau will introduce the integration of AI in MRI-guided Radiotherapy (MRIgRT), discussing algorithm basics, some examples and future challenges. Luise Anna Künzel will provide a comprehensive overview of the MRIgRT workflow, emphasizing the current role of AI in various stages including the possibilities for full automation of the workflow. Guillaume Landry will explore motion management in radiotherapy workflows, highlighting the TrackRAD2025 Challenge for real-time lesion tracking. Finally, Davide Cusumano will present findings from the MESCAL project, evaluating synthetic CT algorithms for MRI-only Radiotherapy. Join us for an in-depth exploration of these cutting-edge topics.

Overview: In this debate 4 renowned clinical physicists will debate whether or not we still need a routine patient/plan specific quality assurance (PSQA) measurements. With the introduction of complex radiotherapy techniques like IMRT, VMAT and stereotactic radiotherapy in the beginning of this century and uncertainties associated with small field dosimetry, MLC modelling in TPS, etc. have increased the demand for PSQA. The provision of commercial PSQA tools lead to intensification of PSQA. PSQA has certainly increased our quality and safety of complex radiotherapy techniques. Over the years, radiotherapy delivery machines have become more stable. Also, treatment planning dose calculations have become more accurate. Moreover, data transfer is exceedingly automated, reducing the chance on human errors. As such, it seems the treatment delivery process might be “in control”. This would mean that, if the treatment techniques are properly commissioned, measurement based PSQA would become less important. Is this true? Come to this debate and let your opinion count! Arguments for and against continued measurement based PSQA will be shared and you can vote who has won the debate.

Overview: Positioning and immobilisation are fundamental steps in the RT patient pathway, uniquely vital for ensuring treatment reproducibility and precision. RTT experts will argue for and against the proposition considering traditional immobilisation strategies in light of advancements such as Surface-Guided Radiotherapy (SGRT), particle therapy, and online ART. Proponents argue that modern technologies and techniques reduce reliance on rigid immobilisation, enhancing patient comfort and experience. Opponents caution against abandoning these proven methods, emphasizing the risks of excess external and internal motion and misalignment without robust positioning systems. Join this engaging session as we discuss the evolving role of immobilisation in RT and its implications for patient care and daily practice.

Overview: Mini-Orals are presented at one of the sessions scheduled in the two mini-oral theatres. Each author will present a 4-slide PowerPoint orally for 4 minutes, followed by 3 minutes for discussion. Sessions will be recorded and made available via the online platform and mobile app.

Overview: Mini-Orals are presented at one of the sessions scheduled in the two mini-oral theatres. Each author will present a 4-slide PowerPoint orally for 4 minutes, followed by 3 minutes for discussion. Sessions will be recorded and made available via the online platform and mobile app.

Overview: Poster Discussions are presented in one of the sessions scheduled at the two poster discussion theatres. Each author will present a digital poster orally for 2 minutes, followed by 2 minutes for discussion. Sessions will be recorded and made available via the online platfrom and mobile app.

Overview: Poster Discussions are presented in one of the sessions scheduled at the two poster discussion theatres. Each author will present a digital poster orally for 2 minutes, followed by 2 minutes for discussion. Sessions will be recorded and made available via the online platfrom and mobile app.