Copenhagen, Denmark
Onsite/Online

ESTRO 2022

Session Item

Saturday
May 07
08:45 - 10:00
Room D1
All the hassle with haematopoietic systems
Bartłomiej Tomasik, Poland;
Dorota Gabrys, Poland
The session will provide a concise overview on a role of radiotherapy in various haematological malignancies. It will start with the discussion on the role of Total Skin Electron Irradiation in patients suffering from non-T-cell lymphomas with extensive skin lesions (Prof. Blamek). This will be followed by the lectures describing a paradigm shift for target definition and dose prescription in radiotherapy of lymphomas with a particular focus on primary mediastinal B-cell lymphomas (Prof. Specht and Prof. Held). The session will end with a thought-provoking lecture featuring the interplay between radiation and CAR T-cell therapy in lymphoma management (Dr Niezink). After the lectures, time for audience discussion will be also provided.
Symposium
Clinical
08:45 - 09:03
TSEI for non-T-cell lymphomas: Previous clinical experience and future needs
Sławomir Blamek, Poland
SP-0025

Abstract

TSEI for non-T-cell lymphomas: Previous clinical experience and future needs
Authors:

Sławomir Blamek1

1Maria Skłodowska-Curie National Research Institute of Oncology, Department of Radiotherapy, Gliwice, Poland

Show Affiliations
Abstract Text

Total Skin Electron Irradiation (TSEI) is a well-established technique of irradiation used in patients
with extensive skin lesions suffering from mycosis fungoides (MF). The response rates are high,
however, the duration of the effect is limited.
There are various implementations of TSEI and probably the most common is called the Stanford
technique. The patient is irradiated from the extended SSD (source to surface distance) and rotated
in six poses to cover the whole skin with the prescribed dose. Due to the continuous demand for
local treatment in MF patients new methods of total skin irradiation emerge like sweeping technique
or irradiation with photons using rotational techniques.
The satisfactory effects of TSEI in patients with MF prompted attempts to use this technique in other
hematologic malignancies associated with extensive skin lesions like non-T-cell lymphomas or even
leukemias.
The summary of indications and outcomes in children and adults will be presented and the possibility
of use of TSEI in non-MF patients discussed.