Copenhagen, Denmark
Onsite/Online

ESTRO 2022

Session Item

Tuesday
May 10
09:15 - 10:30
Room D2
Medical physicists should be directly involved in the design, execution and interpretation of clinical trials
Ane Appelt, United Kingdom;
Sara Pilskog, Norway
4110
Symposium
Physics
10:09 - 10:27
Accreditation for clinical trials: Dosimetry and audits
Catharine Clark, United Kingdom
SP-0983

Abstract

Accreditation for clinical trials: Dosimetry and audits
Authors: Catharine Clark(University College London Hospital, Radiotherapy Physics, London, United Kingdom)
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Purpose or Objective

Dosimetry audit plays an important role in minimising the dosimetric differences between the recruiting centres and ensuring that the patient receives the dose as planned. A reduced uncertainty in dose can lead to a significant reduction in the number of patients required in a randomised controlled trial, thus reducing the cost of the trial. Independent dosimetry audit has been shown many times to identify issues which have either not been seen by the centre, or which are not obvious unless data from several centres is collected. There are multiple methods for carrying out dosimetry audit and in this era of the Covid pandemic these have increasingly included remote or virtual methodologies. Different approaches have different advantages and disadvantages, not least of which include resource and cost. Ideally as much information is collected as possible in advance to ensure that any measurements are as efficient and effective as possible. The role of dosimetry audit in clinical trials also has the benefit of disseminating into routine practice and the consequential reduced variability also raises the standards within the recruiting centres.