Tomotherapy replanning for Head and Neck patients : When? How? Why?
Joao Rodrigues,
Switzerland
PO-1872
Abstract
Tomotherapy replanning for Head and Neck patients : When? How? Why?
1CHUV Lausanne, radio-oncology, Lausanne, Switzerland
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Purpose or Objective
In
our department, H&N patients are mainly treated with tomotherapy. Patients
have up to 33 treatment sessions to complete for a total dose of 69.96 Gy. For
each session, an image merge between the initial planning CT and the MVCT is
performed. RTTs are responsible for ensuring reproducibility throughout
treatment. It is only for the first session that the radiation oncologist
validates the fusion. During the treatment process, visible differences in the
image fusion occur. The doctor is called when the RTTs see a major difference
and assess the need to replan.
Material and Methods
Retrospective analysis of the time between the treatment start date and
the CT replanning date, as well the analysis of the weight change. Reproduction
of the dose distribution on the MVCT of the day before the decision to replan
(on Raystation), and analysis of the differences observed in the dose
distribution, concerning the coverage of PTVs, the dose on OARs and hot/cold possible
areas. New H&N cases that started in a period corresponding to 4 months
will be analyzed.
Results
Of 44 H&N patients, 12 (27%) underwent replanning. The average
weight loss is 2.8 kg. The average number of days elapsed between the treatment
start date and the replanning CT date is 21 days. On the dose distribution
evaluating plans applied on the MVCTs, we observe considerable hot regions at
the PTVs level and therefore also at the skin level with an average relative
max isodose of 111% and absolute max doses up to 78.91 Gy. Generally, the dose
on OARs remains under the dose constraints. On the brachial plexus, we see an
increase that exceeds the dose constraints limits, with D1 max at 70.55 Gy in
one case. Note that these values correspond to a potentially extreme situation,
only if we did not do the replanning. We also see a difference in the volume of
the external contour of the patient, especially in the neck region, with a
visible decrease in the external contour on the MVCT compared to the initial planning
CT.
Conclusion
This
analysis shows the importance of controlling the weight for H&N patients
but also of being vigilant to visible differences on image fusion process. RTTs
should be aware of the potential dosimetric implications demonstrated in this
analysis. The difference observed between the volume of the external contour on
the MVCT and the planning CT, we will call it "intersection volume",
could give us more information for a future analysis, in particular, from what
difference of the "intersection volume” we would have significant
differences (PTV with hot areas, doses on OAR excessive compared to the initial
distribution) and create an indicator to help in the decision to replan or not the
treatment for H&N patients.