Validation of photon convolution-superposition algorithm applied to daily in vivo QC in radiotherapy
grazia Maria Mistretta,
Italy
PO-1642
Abstract
Validation of photon convolution-superposition algorithm applied to daily in vivo QC in radiotherapy
Authors: grazia Maria Mistretta1, Francesca Itta1, Paola Ceroni1, Maria Victoria Gutierrez1, Nicola Maffei1, Federica Campanaro1, Annalisa Bernabei1, Francesco Marino1, Frank Lohr2, Gabriele Guidi1
1University Hospital of Modena, Medical Physics, Modena, Italy; 2University Hospital of Modena, Radiotherapy Unit– Oncology and Hematology, Modena, Italy
Show Affiliations
Hide Affiliations
Purpose or Objective
Implementation of a third-party software for
daily independent in vivo quality control of radiotherapy treatments that
performs calculation of daily fraction doses with a collapsed cone superposition convolution (CCSC) algorithm by using log-file data
and/or EPID doses may further strengthen the QC chain of complex treatment
paradigms. The clinical implementation of such a software, requires an
appropriate study of the applied algorithm. The aim of this
work was the evaluation and validation of the CCSC algorithm of SunNuclear Dose Calculator -DoseCHECK
& PerFRACTION- software, for clinical implementation of daily dosimetrical
QC of radiotherapy treatments.
Material and Methods
The “Raystation” treatment planning system and the “DoseCalculator Algorithm” were
commissioned for use with Elekta VersaHD linear accelerators, with beam
energies of 6, 10, 15 MV, 6 & 10 MV FFF. All measurements were
performed with a water phantom; using Semiflex & PinPoint ionization chambers. Based on international guidelines, several types of treatments
were planned to be delivered in order to evaluate agreement between:
- calculated and measured
point dose in water phantom (IAEA-TECDOC-1540);
- calculated and measured
dose distribution for different complex beams (TG-119) planned with the
techniques IMRT, dMLC and VMAT; Calculated and measured point doses in a
Cheese phantom for different complex beams of different dimensions and for
different dose prescriptions, with targets On Axis and Off Axis;
- calculated and measured
point dose in an inhomogeneous phantom for 3DCRT and VMAT techniques for
different dose prescriptions. The agreement between calculated and
measured dose distributions was performed by using the 2D Array detector
MatriXXEVOLUTION (IBA) and myQA software, using Gamma Index (2mm@ 2%
Global/Local Dose and 3mm@ 3% Global/Local Dose) as comparison index.
Results
Tolerance of all obtained values were inside the evaluation criteria ranges suggested by international guidelines. An excellent agreement was found between point dose calculations and measurements for all energies. Mean relative errors comparing measured doses and Raystation calculations with SDC software were (-0.39±0.95) % and (-0.43±1.05) % respectively for On Axis points (-0.29±0.95) % and (-0.68±0.59) % respectively for Off Axis points. Gamma analysis between SDC calculated and measured dose maps, both with individual passing rates higher than 95%, had a mean excursion difference of (0.33±0.12) % with a Gamma Index 3mm@3% Global Dose. Verification in Cheese and inhomogeneous phantoms showed results inside required tolerances.
Conclusion
Implementation of the “SunCHECK” platform for daily, in-vivo quality control of patient’s radiotherapy treatments is possible, dose calculation results differ only minimally from those of the clinically commissioned reference treatment planning system and correspond thus with dose measurements of plans treated with a regularly functioning Linac.