QA primary program for a skin surface brachytherapy plan
Cecilia Arrichiello,
Italy
PD-0563
Abstract
QA primary program for a skin surface brachytherapy plan
Authors: Cecilia Arrichiello1, Francesca Buonanno2, Gianluca Ametrano1, Federica Gherardi1, Eva Iannacone1, Paolo Muto1
1Istituto Nazionale Tumori - IRCCS - Fondazione G. Pascale, Radiotherapy Unit, Naples, Italy; 2Università degli Studi di Napoli Federico II, Post Graduate School in Medical Physics, Department of Advanced Biomedical Sciences, Naples, Italy
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Purpose or Objective
Among the radiation techniques for cutaneous malignancies treatment, the
choice of brachytherapy is rapidly rising. Last year, in our department, more
than 20 patients were enrolled for skin brachytherapy target. This approach is
especially pointed at large targets or irregularly shaped lesions. Although its
growing development, the AAPM protocols do not comprehensively cover surface
brachytherapy and, currently, no Quality Assurance (QA) guideline are available. The safety and accuracy of delivery is
crucial, since of the lack of well-defined procedures, assuring the real dose
to target correspondence. Skin-brachytherapy workflow may be error prone, with
a wide liability related to the staff experience, especially with personalized
surface mould. Dedicated phantoms for QA are not available, especially for
curved surfaces. Further, in the TPS planning phase, an automatic pre-set for
catheters reconstruction is not available, a manual approach is required.
Material and Methods
Aim of this work was to present a primary approach for a QA skin-plan.
Ten patients (pts) were select for cutaneous brachytherapy with 2÷7 Gy of dose per fraction.
The moulds, holding up to 8 catheters, were settled on a pt specific
thermoplastic mask, to guarantee treatment reproducibility. For each pt a 3D
plan was realized with TPS Oncentra Brachy, based on the TG 43 dose calculation
formalism. A manual reconstruction was used in personalized mould planning. Treatments
were delivered with Flexitron Unit by 192Ir HDR source, driven in
the mould. For all pts, two pre-treatment QAplan were replicated, holding the original
reconstruction. In QAplan1 three random catheters were selected for the
activation of their first dwell position with 15s of transit time. In QAplan2 all
the first positions of catheters were switched-on, with 15s each. The EBT3 radiochromic
films, covering all the catheter tips, were stuck below the tips of catheters
and exposed to each QAplan. Three plans were realized to simulate brachytherpy skin (homogenous,
asymmetric, concave) targets on a water-equivalent phantom, aiming to compare planar
doses with the exposed films placed on
the top of the phantom. EBT3 films were calibrated with 6MV photons and
exposed.
Results
QAplan1 tests the correctness of channel mapping, while QAplan2 shows
the match of blurring outline to the 3D plan rendering, together with the shape
of catheter tips in the mould. The tests performed confirmed the safety of
treatments for all pts and the accuracy of the reconstruction method for all
the plans. An agreement of 10% between measured and planned dose distribution
was found for all the simulation plans.
Conclusion
Waiting for a higher specific QA procedure committed for
skin-brachytherapy, those checks, if performed in a pre-treatment phase,
provide a simple, fast and inexpensive method, that can significantly reduce
serious errors occurrence. This approach can contribute to improve patient
safety and increase the agreement with the required dose distribution.