Preliminary report on Longitudinal Stability of MRI QA up to 2 years on 7 clinical 1.5 T MR-Linacs
Andreas Wetscherek,
United Kingdom
OC-0776
Abstract
Preliminary report on Longitudinal Stability of MRI QA up to 2 years on 7 clinical 1.5 T MR-Linacs
Authors: Andreas Wetscherek1, Erik v.d. Bijl2, Astrid L. H. v. Lier3, Steven Jackson4, Stephen Gibson5, Vivian W. J. v. Pelt6, Signe Winther Hasler7, Rob H.N. Tijssen8
1The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, Joint Dept of Physics, London, United Kingdom; 2Radboud University Medical Center, Dept of Radiation Oncology, Nijmegen, The Netherlands; 3University Medical Center Utrecht, Dept of Radiotherapy, Utrecht, The Netherlands; 4The Christie NHS Foundation Trust, Christie Medical Physics and Engineering, Manchester, United Kingdom; 5Townsville Hospital and Health Service, Townsville Cancer Centre, Townsville, Australia; 6The Netherlands Cancer Institute, Department of Radiation Oncology, Amsterdam, The Netherlands; 7Odense University Hospital, Dept of Oncology, Odense, Denmark; 8Catharina Hospital, Dept of Radiation Oncology, Eindhoven, The Netherlands
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Purpose or Objective
MR-guided
RT leverages the excellent soft-tissue contrast of MRI for daily treatment adaptation,
facilitating hypo-fractionated and dose-escalated treatments. To deliver
precision RT on MR-Linacs, geometric fidelity and long-term stability of MR
imaging components is essential. These components differ from conventional MRI systems
due to the need for radio-translucency and exposure to scattered ionizing
radiation. We report preliminary data on temporal stability of periodic MR
imaging QA on MR-Linacs, which could inform frequency and action levels.
Material and Methods
Seven
centers contributed longitudinal MRI QA data acquired over 3-24 months on their
1.5 T MR-Linac systems (Elekta AB, Stockholm) To ensure consistent data across institutes,
only phantoms provided with the MR-Linac system were used and a prescribed scan
protocol was followed.
A large cylindrical
phantom (37 cm diameter) was used to measure B0 and B1
homogeneity and B0
dependence on gantry position. In addition to a monthly axial measurement,
coronal and sagittal scans were performed every three months. For B0
mapping, phase images were acquired in separate TRs with TE1/TE2=5.4/6.9
ms to minimize phase wrapping, while a double flip angle technique with α1/α2=60°/120° was used for B1 mapping. All tests
were conducted at gantry angle 0° except gantry dependence for which
phase images were acquired without re-shimming at TE=15.7 ms for 13 gantry
angles from -180° to 180°. For a
circular ROI of diameter 35 cm through the isocenter, we report mean, standard
deviation and range from 1st to 99th percentile for each
measurement.
The
vendor-provided PIQT phantom–a multi-purpose phantom with 20 cm diameter, similar
to the ACR phantom–was used for weekly image scaling and SNR tests. Here we report
on flood field uniformity and spatial linearity.
A phantom
consisting of 7 slabs with position markers was used to assess spatial accuracy
of the MR images in a large field of view. We report change in mean and 99th
percentile over time for the distance to known position for markers within a spherical DSV of 35 cm.
Results
Geometric inaccuracy was 0.48±0.24 mm with the 99th percentile being 1.21 mm. Results were very stable over time, with an average intra-site standard deviation of 0.03 mm.
For one system, PIQT analysis found SNR decline of the transmit body coil, which was replaced after 10 months of operation. Mean values post-replacement differed significantly (p<0.0001).
Conclusion
The
vendor-provided PIQT tests capture many parameters that can reveal performance decline
of components, but measurements are limited to a small field of view.
Considering the dosimetric importance of the patient outline, larger phantoms
are required to characterize the geometric accuracy of the MR images. We found
all QA tests highly stable over time unless hardware components were exchanged.
Most tests were highly comparable between sites with the exception of B0
homogeneity as a function of gantry angle due to site-specific shimming.