Camera-based in-vivo dosimetry using dual-material 3D printed scintillator arrays
OC-0617
Abstract
Camera-based in-vivo dosimetry using dual-material 3D printed scintillator arrays
Authors: Nicholas Lynch1, Thalat Monajemi2, James Robar2
1Dalhousie University, Physics & Atmospheric Science, Halifax, Canada; 2Dalhousie University, Radiation Oncology, Halifax, Canada
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Purpose or Objective
To describe a methodology for the dual-material fused deposition modeling (FDM) 3D printing of plastic scintillator arrays, to characterize their light output under irradiation using an sCMOS camera, and to establish a methodology for their dosimetric calibration.
Material and Methods
We have published an investigation into
the fabrication and characterization of single element FDM printed
scintillators with the goal of producing customizable dosimeters for radiation
therapy applications. This work builds on previous investigations
by extending the concept to the production of high resolution (scintillating
element size 3 mm³) planar and curved scintillator arrays (Fig. 1A/1B).
The arrays were fabricated using a BCN3D Epsilon W27 3D printer and are composed
of polylactic acid (PLA) filament and BCF-10 plastic scintillator (Saint Gobain
Crystals, Ohio, USA).
The light signals emitted from both
arrays under irradiation were imaged using 10 ms exposures from a 16-bit PCO Panda 4.2 sCMOS camera (PCO
Photonics Ltd., Ontario, Canada) positioned at the foot of the treatment couch
(210 cm from array). 6 MV photon fields (Truebeam, Varian, Palo Alto, USA) were
delivered using gantry and collimator angles of 0°,
100 Monitor Units, field size of 20 x 20 cm², dose rate of 600
MU/min and source-to-surface distance of 100 cm. Each array was placed
vertically on 10 cm slab of solid water with the beam incident on the top of
each array (Fig. 1C/1D).
The collected images were processed
using a purpose-built MATLAB program to correct for known optical aretfacts and
determine the light output for each scintillating element (Fig. 2A). Element-to-element sensitivity was investigated
by exposing individual elements to an identical known dose under uniform scatter
conditions. Following correction for sensitivity, the light output for the planar
array was compared to Radiochromic
film and Monte Carlo simulations based on geometric and material information
obtained from the arrays 3D print model.
Results
The results establish the feasibility of dual-material 3D printing for
the fabrication of patient-specific plastic scintillator arrays and demonstrate
that they provide sufficient signal in response to therapeutic doses. However, the
3D printed scintillating elements were found to possess a non-uniform
sensitivity with an average element to element sensitivity difference of 2.6%. Following
sensitivity correction, planar array measurements compared favorably with Monte
Carlo simulations (Fig.
2B).
Conclusion
In this study we developed and characterized 3D printed arrays of plastic scintillators and demonstrated a methodology for dosimetric calibration of simple geometries. Monte Carlo simulations suggest the possibility of array sensitivity corrections without need for pre-treatment irradiation.