Evidence Based Radiation Oncology

Montpellier, France

[ Early deadline: 23 March 2019 ]
[ Target volumes ]

This course is aimed primarily at trainee radiation oncologists. It may also be of interest to medical physicists and technologists who would like an overview of current clinical practice in the major treatment sites.

Course Directors 

  • Bernard Dubray, Radiation Oncologist, Centre Henri Becquerel, Rouen (FR) 

  • Johannes Kaanders, Radiation Oncologist, Radboud University Nijmegen Medical Centre, Nijmegen (NL)


  • Berardino De Bari, Radiation Oncologist, Centre Hospitalier Régional Universitaire de Besançon, Besançon (FR) 

  • Youlia Kirova, Radiation Oncologist, Marie Curie Institute, Paris (FR) 

  • Gian Carlo Mattiucci, Radiation Oncologist, Università Cattolica del Sacro Cuore, Rome (IT) 

  •  Li Tee Tan, Radiation Oncologist, Addenbrookes Hospital – Oncology Centre, Cambridge (UK) 

  • Matt Williams, Consultant Clinical Oncologist, Charing Cross Hospital, London (UK)

Local organiser 

  • David Azria, Radiation Oncologist, SIRIC Montpellier Cancer, Montpellier

The course focuses on the concept of evidence-based medicine and describes the methodology underlying clinical research. Areas of biomedical statistics necessary for participants to develop skills of critical reading and presentation of research evidence will be covered.The course will explore the state-of-the-art of radiation therapy in the major tumour sites: breast, oesophagus and stomach, rectum, prostate, head and neck, lung, CNS and gynaecological malignancies. A separate session will deal with the major issues in palliative radiation therapy. The clinical component of the course will comprise a combination of lectures and case discussions. Participants will have the opportunity to discuss clinical scenarios in small groups before the management options are then discussed in the light of the research evidence in plenary sessions.

Learning outcomes

By the end of this course participants should be able to:

  • Define the hierarchy of evidence and use this to evaluate the basis of radiation treatment protocols
  • Identify areas of uncertainty in daily radiotherapy practice 
  • Describe the statistical basis for the design of clinical trials and critically appraise the published literature 
  • Identify those aspects of current radiotherapy practice which are supported by the highest levels of evidence and those which are not 
  • Outline the evidence supporting the use of altered fractionation regimens and combined-modality treatment 
  • Critically evaluate an oral or written scientific presentation.

Course content

  • General introduction to evidence-based medicine 
  • The terminology of radiation therapy, errors and uncertainties in daily practice 
  • Statistics for the radiation oncologist, how to describe and interpret data from clinical trials and meta-analyses 
  • Prostate cancer 
  • Lung cancer 
  • Rectal cancer 
  • Head and neck cancer 
  • CNS malignancies 
  • Gynaecological malignancies 
  • Breast cancer 
  • Gastric and oesophageal cancer 
  • Radiation therapy in palliative care.


Before commencing this course participants should: 

  • Review their institution’s radiotherapy treatment protocols in those areas covered by this course and be prepared to apply and discuss these in case discussions 
  • Try to distinguish those areas of their practice that can be justified by the available evidence from those where the evidence-basis is uncertain 
  • Be prepared to ask questions and contribute to discussions.

Teaching methods

  • 31 hours of lectures and case-based discussion 
  • 9 hours of case-based discussion in small groups.

The faculty will present a summary of the available evidence underlying current radiotherapy practice in the major treatment sites and will identify and discuss those areas of practice for which the evidence remains limited. The application of scientific evidence to clinical practice will be illustrated through the use of case-based discussions in which participants will be encouraged to discuss and present practical solutions to clinical scenarios.

Mehods of assessment

  • MCQ  
  • Evaluation form.




Please find the draft version of the course programme here. ESTRO holds the right to change it without any prior notice.

Key words

Evidence-based medicine, quality of evidence, descriptive statistics, clinical trial, meta-analysis, statistical significance, clinical significance, error, bias, randomisation, stratification, endpoints, uncertainties in clinical practice, therapeutic ratio (gain), target volumes, GTV, CTV, PTV, external beam radiotherapy, brachytherapy, imageguided radiotherapy (IGRT), intensitymodulated radiotherapy (IMRT), prostate cancer, lung cancer, rectal cancer, head and neck cancer, breast cancer, gynaecological cancer, gastric cancer, oesophageal cancer, CNS malignancies, palliation in advanced and metastatic disease.

Further reading / web resources

Please consult the ESTRO website page of this course for further information.


Application for CME recognition will be submitted to the European Accreditation Council for Continuing Medical Education (EACCME), an institution of the European Union of Medical Specialists (UEMS). EACCME credits are recognised by the American Medical Association towards the Physician’s Recognition Award (PRA). Information on the status of the applications can be obtained from the ESTRO offic


The course will be held in one of the campuses of Institut du Cancer de Montpellier (ICM): 
208, Avenue des Apothicaires 
Parc Euromédecine 
34298 Montpellier


We would recommend that you would search suitable accommodation through one of the online booking websites.  ESTRO will not be providing any accommodation solutions.


ESTRO members can order products at substantially reduced prices. Please note that in order to benefit from the member price, you must renew your membership for 2019 before registering to the course.To benefit from these member rates, please visit the membership page to become a member or renew your membership BEFORE proceeding with your order.



Early rate

Late rate

In-training members* 450 EUR 625 EUR
Members 600 EUR 725 EUR
Non Members 750 EUR 850 EUR

* Members with specialty RadiationTherapist (RTT) may register at the In Training fee

Early rates are applied up to three months before the starting date of the course. 
Late rates are applied three months before the starting date of the course.

The fee includes the course material, coffees, lunches, and the social event.

Advance registration & payment are required.

On-site registration will not be available.

Since the number of participants is limited, late registrants are advised to contact the ESTRO office before payment, to inquire about availability of places. Access to homework and/or course material will become available upon receipt of full payment.


Insurance and cancellation


The organiser does not accept liability for individual medical, travel or personal insurance. Participants are strongly advised to take out their own personal insurance policies.   
In case an unforeseen event would force ESTRO to cancel the meeting, the Society will reimburse the participants fully the registration fees. ESTRO will not be responsible for the refund of travel and accommodation costs.

In case of cancellation, full refund of the registration fee minus 15% for administrative costs may be obtained up to three months before the course and 50% of the fee up to one month before the course. No refund will be made if the cancellation request is postmarked less than one month before the start of the course.

Reduced fees

ESTRO members from economically challenged countries may register at a preferential rate of 350 Euro if three conditions are met:

  1. Only ESTRO members for 2019 are eligible (please make sure your 2019 membership is in order before you apply for the reduced fees)
  2. Only one course per person per year can be subsidized by ESTRO
  3. Sponsored candidates are not entitled to reduced fees (the invoicing address has to be the one of the participant)  

Please note: 

  • We can only guarantee a certain number of reduced fees per course
  • Application deadlines are the same as early registration fees (3 months before the course date

List of Economically challenged countries and eligible courses 


Many of our course participants are able to find full or partial funding from sources available locally. 

For more please go to: GRANTS

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