ESTRO 2023

Session Item

Tuesday

May 16

11:00 - 12:15

Strauss 1

What’s new in particle therapy?

Co-Chair: Villads Lundsteen Jacobsen, Denmark;

Chair: , Switzerland

Overview: Although particle therapy (PT) is usually considered as the minority in the RT society, the research activities in PT are always sparkling and dynamic. With the joint efforts among the key PT centres in EU and worldwide, the important achievements from RAPTOR consortium will be updated foremost. First, the challenges and solutions for online adaptive PT will be discussed from all aspects of the entire workflow. Then, towards intra-fractional motion, the practical solution and outstanding technical gaps will be presented with a particular rising focus on the longitudinal motion effects. Next, the potential of AI for solving these long-standing PT problems will be elucidated, and attendant challenges on model validation and clinical implementation will be emphasised. Finally, an overview of proton FLASH will be given from aspects of technical realisation, dosimetry, radiobiology and treatment planning.

Session Type: Symposium

Track: Physics

Journey:

11:54 - 12:12

Proton-FLASH

Speaker: Per Poulsen, Denmark

Presentation Number: SP-1045

Abstract

Abstract Title:

Proton-FLASH

Authors:

Per Poulsen¹

¹Aarhus University Hospital, Danish Center for Particle Therapy, Aarhus, Denmark

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Abstract Text

FLASH is radiotherapy delivered with ultra-high dose rates that are hundreds of times higher than in conventional radiotherapy. It has received massive interest since pre-clinical experiments have shown a preferential sparing of healthy tissue with maintained effects on tumors. Most experiments have used electron beams with shallow treatment depths of a few centimeters. FLASH dose rates can also be obtained with high energy proton beams at clinical proton facilities, which allows treatment in any relevant tumor depth. In this lecture, a brief overview of proton FLASH will be given including realization of FLASH dose rates with proton beams, proton FLASH dosimetry, treatment planning and pre-clinical studies at the Danish Center for Particle Therapy.