In general, QLQ-C30 functional scores before RT were satisfactory and symptom scores were sparse. QLQ-C30 symptom scores before RT were also sparse except urinary symptoms. The sexual functional scores were modest, probably due to the old age (median 74).
At RT end, there was a slight decline of role functional scores and a remarkable increase of symptom scores in terms of fatigue, loss of appetite and incontinence aid. The decline of other functional scores were moderate. The increase of other symptom scores were also moderate except insomnia and diarrhoea, which even presented a decrease.
Three months after RT, physical and sexual function almost recovered to their baseline level and sexual activity recovered only partially, while role function remained stable. Interestingly, general healthy status, cognitive, emotional and social function increase over its baseline. Most symptoms largely relieved, while fatigue, nausea/vomiting only partially relieved. Interestingly, pain, dyspnoea and financial difficulties improved over baseline. Incontinence aid, insomnia and hormonal treatment-related symptoms went worse.
One year after RT, most functional and symptom scores remained stable compared to the previous time point. However, GHS, emotional function, cognitive function, social function, diarrhoea, urinary and bowel symptoms turned better over baseline while role function, fatigue, constipation, insomnia further went worse. Two year after RT, almost all the functional and symptom scores remained stable compared to the one-year time point except insomnia, which went a little worse.