Session

Overview: In patients with high-risk prostate cancer, radical radiotherapy combined with long-term androgen deprivation has been demonstrated to offer excellent long-term outcomes. Due to the risk of occult microscopic nodal metastases, elective whole pelvis nodal radiotherapy (WPRT) is often proposed for these patients for improving long-term disease control. Although modern radiotherapy techniques allow more conformal and less toxic pelvic treatments, concerns about the potential benefits of WPRT still exist. Available retrospective and prospective literature data on the role of WPRT for high-risk prostate cancer patients will be discussed and commented, focusing on the impact of modern imaging modalities, advanced radiotherapy techniques, and genomic.