Dr. Willey is the Hale-Stephens ROAR Endowed Chair for Distinctive Radiation Research at The University of Alabama at Birmingham (USA). He is a physician-scientist in the O’Neal Comprehensive Cancer Center. Dr. Willey’s clinical expertise is in central nervous system, head and neck, and lung malignancies using fractionated and radiosurgery techniques. He has secondary faculty appointments within Cell, Developmental and Integrative Biology, Biochemistry and Molecular Genetics, Biomedical Engineering, and the UAB Center for Clinical and Translational Science. His research interests include signal transduction, particularly with kinase driven cascades, and radiation response pathways in a variety of cancers, including gliomas, lung cancer, and head and neck cancers. In the area of kinase signaling, Dr. Willey is the Director of the UAB Kinome Core that performs global kinase signaling analysis using a high-content peptide substrate microarray platform. This facility has been used for molecular profiling/subtyping and to identify and examine kinase drivers involved in several disease processes ranging from autoimmune disease, psychiatric illness, and numerous cancers. The UAB Kinome Core has been a featured tool for studies involving Glioblastoma (GBM) patient-derived xenografts (PDX), which are being used for biomarker testing and drug development. Most recently, his work has focused on miniaturization strategies for GBM PDX tumors for high-throughput therapy testing and molecular testing at the transcriptome and kinome levels. Dr. Willey is the contact Principal Investigator for an NIH U01 consortium grant which is comparing patient-derived models of GBM including 3D bioprinted models.